High Content Analysis of Primary Macrophages Hosting Proliferating Leishmania Amastigotes: Application to Anti-leishmanial Drug Discovery
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چکیده
منابع مشابه
High Content Analysis of Primary Macrophages Hosting Proliferating Leishmania Amastigotes: Application to Anti-leishmanial Drug Discovery
BACKGROUND/OBJECTIVES Human leishmaniases are parasitic diseases causing severe morbidity and mortality. No vaccine is available and numerous factors limit the use of current therapies. There is thus an urgent need for innovative initiatives to identify new chemotypes displaying selective activity against intracellular Leishmania amastigotes that develop and proliferate inside macrophages, ther...
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ژورنال
عنوان ژورنال: PLoS Neglected Tropical Diseases
سال: 2013
ISSN: 1935-2735
DOI: 10.1371/journal.pntd.0002154